We did tons of Duriel Runs with different classes. Here is everything we learned about all the Uber Uniques in Diablo 4.
Interesting Droprate Theorys
There is a slight difference in the drop chances while Bobs have a slightly harder time getting Sho because they have both the Grandfather and the Doombringer in the loot table, so that makes it a bit harder, we think it's like one in 300 to find a Shako and bar while in other classes such as sorc it's one in 250 because you only have five Uber uniques in the pool, you can drop Shako, you can drop Andariel, you can't drop Doombringer, you can't drop grandfather, you can drop Starless Skies, Melted Heart of Selig and Ahavarion Spear of Lycander, so that's only five while Bob and necro have six in that D table, so if you're still missing a Shako, maybe you want to consider playing on a sorcerer or on a druid for that matter and even the Rogue only has Doombringer in the root table, but has no grandfather and has no staff.
Droprate
We basically confirmed that the drop rate is about 2%, so it will take you about 50 runs to get an Uber Unique and about 250 to get the Uber Unique that you want on average, it's never guaranteed it might take you way longer, it took us a couple of thousand runs before we even got them Mard, but that was most likely just due to very bad RNG, so you can get L unlucky, but you can also get very lucky and just get to the Uber unique that you want very early on, but even if you have only one or two of these Uber Uniques, and you still have some time to get your hands on some, it's we think like another 10 days before the Abattoir of Zir Prediction comes out, and again we don't even know if these will be like necessary or any required even we really hope on the high end yes you will need some of these toughnesses but like the early levels, everybody can manage cuz, the tier one of Abattoir of Zir Prediction is basically the equivalent of nightmare dungeon 100.
Tips
We think a lot of builds and classes definitely can do this without having any of the Uber Uniques, but if you have some time, and if you want to prepare for the new end game, we highly encourage you play some D runs gather your friends do some hell ties do some bounties.
[Berserker Axe]
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